Cancer immunotherapy can cause side effects whose details are buried in clinical notes. A new Nature Cancer study tests an AI system that highlights evidence for six types of immune-related adverse events, helping staff review the records.

In a randomized crossover study with 17 clinical research staff, assistance cut annotation time by about 2.7 minutes per note, with improvements in accuracy and agreement. A separate three-month silent deployment tested performance on incoming notes.

This is evidence for assisted record review. The study did not establish better patient outcomes, and the authors call for external validation.

Public code